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primary murine microglia  (Creative Bioarray Inc)

 
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    Creative Bioarray Inc primary murine microglia
    Primary Murine Microglia, supplied by Creative Bioarray Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/primary murine microglia/product/Creative Bioarray Inc
    Average 90 stars, based on 1 article reviews
    primary murine microglia - by Bioz Stars, 2026-03
    90/100 stars

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    TLR4C inhibited the secretion of IL-6, TNF-α and MCP-1 in <t>primary</t> <t>murine</t> <t>microglia</t> <t>cells.</t> Cells were incubated for 2 h with 20 μm concentrations of the indicated peptides, then washed and stimulated with 10 μm Aβ for 24 h. Secreted levels of IL-6 (A), TNF-α (B), and MCP-1 (C) in the supernatant were assessed by ELISA. The results are the mean ± S.E. of 3 independent experiments and are normalized to Aβ for each cytokine as follows: IL-6, 304.98 ± 13.42 pg/ml; TNF-α, 732.137 ± 250pg/ml; MCP-1, 620.49 ± 20.57 pg/ml. ***, p < 0.005, 3 repeats for each experiment.
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    TLR4C inhibited the secretion of IL-6, TNF-α and MCP-1 in <t>primary</t> <t>murine</t> <t>microglia</t> <t>cells.</t> Cells were incubated for 2 h with 20 μm concentrations of the indicated peptides, then washed and stimulated with 10 μm Aβ for 24 h. Secreted levels of IL-6 (A), TNF-α (B), and MCP-1 (C) in the supernatant were assessed by ELISA. The results are the mean ± S.E. of 3 independent experiments and are normalized to Aβ for each cytokine as follows: IL-6, 304.98 ± 13.42 pg/ml; TNF-α, 732.137 ± 250pg/ml; MCP-1, 620.49 ± 20.57 pg/ml. ***, p < 0.005, 3 repeats for each experiment.
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    TLR4C inhibited the secretion of IL-6, TNF-α and MCP-1 in primary murine microglia cells. Cells were incubated for 2 h with 20 μm concentrations of the indicated peptides, then washed and stimulated with 10 μm Aβ for 24 h. Secreted levels of IL-6 (A), TNF-α (B), and MCP-1 (C) in the supernatant were assessed by ELISA. The results are the mean ± S.E. of 3 independent experiments and are normalized to Aβ for each cytokine as follows: IL-6, 304.98 ± 13.42 pg/ml; TNF-α, 732.137 ± 250pg/ml; MCP-1, 620.49 ± 20.57 pg/ml. ***, p < 0.005, 3 repeats for each experiment.

    Journal: The Journal of Biological Chemistry

    Article Title: Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration

    doi: 10.1074/jbc.M117.784983

    Figure Lengend Snippet: TLR4C inhibited the secretion of IL-6, TNF-α and MCP-1 in primary murine microglia cells. Cells were incubated for 2 h with 20 μm concentrations of the indicated peptides, then washed and stimulated with 10 μm Aβ for 24 h. Secreted levels of IL-6 (A), TNF-α (B), and MCP-1 (C) in the supernatant were assessed by ELISA. The results are the mean ± S.E. of 3 independent experiments and are normalized to Aβ for each cytokine as follows: IL-6, 304.98 ± 13.42 pg/ml; TNF-α, 732.137 ± 250pg/ml; MCP-1, 620.49 ± 20.57 pg/ml. ***, p < 0.005, 3 repeats for each experiment.

    Article Snippet: Primary murine microglia Cells were purchased from ScienCell Research Laboratories.

    Techniques: Incubation, Enzyme-linked Immunosorbent Assay